| Modification Notes |
DIP2C (disco-interacting protein 2 homolog C) is a 1,556 amino acid protein. It is one of three human homologs of the Drosophila dip2 (disconnected-interacting protein 2) protein. In Drosophila, dip2 interacts with disco, a protein required for neuronal connections in the visual systems of larvae and adults. The closest vertebrate homologs to disco are the basonuclin genes. In mice, DIP2 homologs show restricted expression to the brain. This suggests that, similar to the function of Drosophila dip2, vertebrate DIP2 homologs (DIP2A, DIP2B and DIP2C) may play a role in the development of the nervous system. |