Application
Western blot analysis of RASSF3 expression in non-transfected: (A) and mouse RASSF3 transfected: (B) 293T whole cell lysates.Application
Western blot analysis of RASSF3 expression in non-transfected: (A) and mouse RASSF3 transfected: (B) 293T whole cell lysates.Application
Western blot analysis of RASSF3 expression in non-transfected: (A) and mouse RASSF3 transfected: (B) 293T whole cell lysates.| Product Name | RASSF3 Antibody (H-60) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Ras is a small GTP-binding protein involved in many cellular processes, including proliferation, differentiation and apoptosis. Ras transmits signals of cell surface receptors by binding to a variety of effector molecules. In addition to the well characterized effectors Raf and PI 3-kinase, Ras also interacts with members of the RASSF family, including RASSF1, RASSF2, RASSF3, RASSF4 and Nore1. Members of the RASSF family contain a highly conserved Ras association domain (Ral GDS/AF-6 or RA) and function as Ras effectors/tumor suppressors. RASSF3 (Ras association domain family 3) is a ubiquitously expressed protein found in normal and cancerous tissues. RASSF3 contains an N-terminal RA domain and a coiled-coil SARAH domain. Three isoforms, namely RASSF3A, RASSF3B and RASSF3C, may exist for RASSF3 due to alternative splicing. RASSF3B and RASSF3C are shorter than RASSF3A and do not contain the RA and SARAH domain. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of RASSF3 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including bovine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 21-80 mapping near the N-terminus of RASSF3 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 21-80 mapping near the N-terminus of RASSF3 of human origin |
| Entrez Gene | 283349 |
|---|
Application
Western blot analysis of RASSF3 expression in non-transfected: (A) and mouse RASSF3 transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of RASSF3 expression in non-transfected: (A) and mouse RASSF3 transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of RASSF3 expression in non-transfected: (A) and mouse RASSF3 transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of RASSF3 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including bovine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
