Application
Western blot analysis of MAGG1 Antibody (C-term) in mouse lung tissue lysates (35ug/lane). MAGG1 (arrow) was detected using the purified Pab.| Product Name | MAGG1 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:50~100 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | HCA4, MAGEG1 |
|---|---|
| Alternative Names | NDNL2 HCA4 MAGEG1 Melanoma-associated antigen G1 Hepatocellular carcinoma-associated protein 4 MAGE-G1 antigen Necdin-like protein 2 |
| Molecular Weight(MW) | 34308 Da |
| Function | Component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies (APBs). In vitro enhances ubiquitin ligase activity of NSMCE1. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. May be a growth suppressor that facilitates the entry of the cell into cell cycle arrest |
| Tissue Specificity | Ubiquitous. |
| Cellular Localization | Cytoplasm (By similarity). Nucleus. Chromosome, telomere (Probable) |
| Entrez Gene | 56160 |
|---|
Application
Western blot analysis of MAGG1 Antibody (C-term) in mouse lung tissue lysates (35ug/lane). MAGG1 (arrow) was detected using the purified Pab.| Application Notes | WB:1:50~100 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
