Application
A. Western blot analysis on Jurkat cell lysate using anti-MALT1 (N-term) RabMAb (Cat. #AJ1454a), dilution 1:2,000.| Product Name | MALT1 (MLT1) Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Monoclonal |
|---|---|
| Clone Number | EP603Y |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~2000 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | MLT |
|---|---|
| Alternative Names | MALT1 MLT Mucosa-associated lymphoid tissue lymphoma translocation protein 1 MALT lymphoma-associated translocation Paracaspase |
| Molecular Weight(MW) | 92272 Da |
| Function | Enhances BCL10-induced activation of NF-kappa-B. Involved in nuclear export of BCL10. Binds to TRAF6, inducing TRAF6 oligomerization and activation of its ligase activity. Has ubiquitin ligase activity. MALT1-dependent BCL10 cleavage plays an important role in T-cell antigen receptor-induced integrin adhesion |
| Tissue Specificity | Highly expressed in peripheral blood mononuclear cells. Detected at lower levels in bone marrow, thymus and lymph node, and at very low levels in colon and lung |
| Cellular Localization | Cytoplasm, perinuclear region. Nucleus. Note=Shuttles between the nucleus and cytoplasm. Found in perinuclear structures together with BCL10 |
| Entrez Gene | 10892 |
|---|
Application
A. Western blot analysis on Jurkat cell lysate using anti-MALT1 (N-term) RabMAb (Cat. #AJ1454a), dilution 1:2,000.| Application Notes | WB:1:500~2000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
