Application
MANF Antibody (N-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the MANF antibody detected the MANF protein (arrow).| Product Name | MANF Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | ARMET, ARP |
|---|---|
| Alternative Names | MANF ARMET ARP Mesencephalic astrocyte-derived neurotrophic factor Arginine-rich protein Protein ARMET |
| Molecular Weight(MW) | 20700 Da |
| Function | Selectively promotes the survival of dopaminergic neurons of the ventral mid-brain. Modulates GABAergic transmission to the dopaminergic neurons of the substantia nigra. Enhances spontaneous, as well as evoked, GABAergic inhibitory postsynaptic currents in dopaminergic neurons (By similarity). Inhibits cell proliferation and endoplasmic reticulum (ER) stress-induced cell death |
| Tissue Specificity | This MANF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 19-48 amino acids from the N-terminal region of human MANF. |
| Cellular Localization | Secreted. |
| Entrez Gene | 7873 |
|---|---|
| Nucleotide Accession | NP_006001.3 |
Application
MANF Antibody (N-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the MANF antibody detected the MANF protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
