Application
Western blot analysis of MAP-EB3 Antibody (Center) in mouse brain tissue lysates (35ug/lane). MAP-EB3 (arrow) was detected using the purified Pab.Application
Formalin-fixed and paraffin-embedded human skeletal muscle with MAP-EB3 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.| Product Name | MAP-EB3 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MAPRE3; Microtubule-associated protein RP/EB family member 3; EB1 protein family member 3; End-binding protein 3; RP3 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | MAPRE3 Microtubule-associated protein RP/EB family member 3 EB1 protein family member 3 End-binding protein 3 RP3 |
|---|---|
| Molecular Weight(MW) | 31982 Da |
| Function | Binds to the plus end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes microtubule growth. May be involved in spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration (By similarity) |
| Tissue Specificity | Predominantly expressed in brain and muscle. |
| Cellular Localization | Cytoplasm, cytoskeleton. Note=Associated with the microtubule network. Detected at the plus end of microtubules |
| Entrez Gene | 22924 |
|---|
Application
Western blot analysis of MAP-EB3 Antibody (Center) in mouse brain tissue lysates (35ug/lane). MAP-EB3 (arrow) was detected using the purified Pab.
Application
Formalin-fixed and paraffin-embedded human skeletal muscle with MAP-EB3 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
