Application
LZK Antibody (C-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the LZK antibody detected the LZK protein (arrow).Application
MAP3K13 (LZK) Antibody (C-term) (S869) immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MAP3K13 (LZK) Antibody (C-term) (S869) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | MAP3K13 (LZK) Antibody (C-term) (S869) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | LZK |
|---|---|
| Alternative Names | MAP3K13 LZK Mitogen-activated protein kinase kinase kinase 13 Leucine zipper-bearing kinase Mixed lineage kinase |
| Molecular Weight(MW) | 108296 Da |
| Function | Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. Acts synergistically with PRDX3 to regulate the activation of NF-kappa-B in the cytosol. This activation is kinase-dependent and involves activating the IKK complex, the IKBKB-containing complex that phosphorylates inhibitors of NF-kappa-B |
| Tissue Specificity | Expressed in the adult brain, liver, placenta and pancreas, with expression strongest in the pancreas |
| Cellular Localization | Cytoplasm. Membrane; Peripheral membrane protein |
| Entrez Gene | 9175 |
|---|
Application
LZK Antibody (C-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the LZK antibody detected the LZK protein (arrow).
Application
MAP3K13 (LZK) Antibody (C-term) (S869) immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MAP3K13 (LZK) Antibody (C-term) (S869) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
