MAP3K7IP3 Antibody (N-term) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the MAP3K7IP3 antibody detected the MAP3K7IP3 protein (arrow).
TAB3; MAP3K7IP3; TGF-beta-activated kinase 1 and MAP3K7-binding protein 3; Mitogen-activated protein kinase kinase kinase 7-interacting protein 3; NF-kappa-B-activating protein 1; TAK1-binding protein 3; TGF-beta-activated kinase 1-binding protein 3
Key Feature
Clonality
Polyclonal
Isotype
Ig
Host Species
Rabbit
Tested Applications
WB
WB:1:100~500
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
MAP3K7IP3
Alternative Names
TAB3 MAP3K7IP3 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 NF-kappa-B-activating protein 1 TAK1-binding protein 3 TGF-beta-activated kinase 1-binding protein 3
Molecular Weight(MW)
78683 Da
Function
Adapter linking MAP3K7/TAK1 and TRAF6 or TRAF2. Mediator of MAP3K7 activation, respectively in the IL1 and TNF signaling pathways. Plays a role in activation of NF-kappa-B and AP1 transcription factor. Isoform 2 may be an oncogenic factor
Tissue Specificity
Widely expressed. Constitutively overexpressed in certain tumor tissues. Isoform 1 is a major transcript while isoform 2 is a minor transcript
MAP3K7IP3 Antibody (N-term) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the MAP3K7IP3 antibody detected the MAP3K7IP3 protein (arrow).
Application Notes
WB:1:100~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.