Application
MAPKSP1 Antibody (N-term) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the MAPKSP1 antibody detected the MAPKSP1 protein (arrow).| Product Name | MAPKSP1 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | LAMTOR3; MAP2K1IP1; MAPKSP1; Ragulator complex protein LAMTOR3; Late endosomal/lysosomal adaptor and MAPK and MTOR activator 3; MEK-binding partner 1; Mitogen-activated protein kinase kinase 1-interacting protein 1; Mitogen-activated protein kinase scaffol |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | MAP2K1IP1 MAPKSP1 |
|---|---|
| Alternative Names | LAMTOR3 MAP2K1IP1 MAPKSP1 Ragulator complex protein LAMTOR3 Late endosomal/lysosomal adaptor and MAPK and MTOR activator 3 MEK-binding partner 1 Mitogen-activated protein kinase kinase 1-interacting protein 1 Mitogen-activated protein kinase scaffol |
| Molecular Weight(MW) | 13623 Da |
| Function | As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. Adapter protein that enhances the efficiency of the MAP kinase cascade facilitating the activation of MAPK2 |
| Tissue Specificity | This MAPKSP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human MAPKSP1. |
| Cellular Localization | Late endosome membrane; Peripheral membrane protein; Cytoplasmic side (By similarity) |
| Entrez Gene | 8649 |
|---|---|
| Nucleotide Accession | NP_068805.1 |
Application
MAPKSP1 Antibody (N-term) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the MAPKSP1 antibody detected the MAPKSP1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
