Application
MARCH4 Antibody (C-term) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the MARCH4 antibody detected the MARCH4 protein (arrow).| Product Name | MARCH4 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MARCH4; KIAA1399; RNF174; E3 ubiquitin-protein ligase MARCH4; Membrane-associated RING finger protein 4; Membrane-associated RING-CH protein IV; RING finger protein 174 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | KIAA1399 RNF174 |
|---|---|
| Alternative Names | MARCH4 KIAA1399 RNF174 E3 ubiquitin-protein ligase MARCH4 Membrane-associated RING finger protein 4 Membrane-associated RING-CH protein IV RING finger protein 174 |
| Molecular Weight(MW) | 45528 Da |
| Function | E3 ubiquitin-protein ligase that may mediate ubiquitination of MHC-I and CD4, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin- conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates |
| Tissue Specificity | Expressed in brain and placenta. |
| Cellular Localization | Golgi apparatus membrane; Multi-pass membrane protein |
| Entrez Gene | 57574 |
|---|---|
| Nucleotide Accession | NP_065865.1 |
Application
MARCH4 Antibody (C-term) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the MARCH4 antibody detected the MARCH4 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
