Application
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.Application
MARK3 Antibody (S569) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the MARK3 antibody detected the MARK3 protein (arrow).| Product Name | MARK3 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MARK3; CTAK1; EMK2; MAP/microtubule affinity-regulating kinase 3; C-TAK1; Cdc25C-associated protein kinase 1; ELKL motif kinase 2; Protein kinase STK10; Ser/Thr protein kinase PAR-1; Serine/threonine-protein kinase p78 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | IHCWB |
| IHC:1:50~100 WB |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CTAK1 EMK2 |
|---|---|
| Alternative Names | MARK3 CTAK1 EMK2 MAP/microtubule affinity-regulating kinase 3 C-TAK1 Cdc25C-associated protein kinase 1 ELKL motif kinase 2 Protein kinase STK10 Ser/Thr protein kinase PAR-1 Serine/threonine-protein kinase p78 |
| Molecular Weight(MW) | 84489 Da |
| Function | Involved in the specific phosphorylation of microtubule- associated proteins for tau, MAP2 and MAP4. Phosphorylates CDC25C on 'Ser-216'. Regulates localization and activity of some histone deacetylases by mediating phosphorylation of HDAC7, promoting subsequent interaction between HDAC7 and 14-3-3 and export from the nucleus |
| Tissue Specificity | Ubiquitous. |
| Cellular Localization | Cell membrane; Peripheral membrane protein. |
| Entrez Gene | 4140 |
|---|
Application
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Application
MARK3 Antibody (S569) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the MARK3 antibody detected the MARK3 protein (arrow).| Application Notes | IHC:1:50~100 WB |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
