Application
MAS1 Antibody (C-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the MAS1 antibody detected the MAS1 protein (arrow).| Product Name | MAS1 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MAS1; MAS; Proto-oncogene Mas |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | MAS |
|---|---|
| Alternative Names | MAS1 MAS Proto-oncogene Mas |
| Molecular Weight(MW) | 37465 Da |
| Function | Receptor for angiotensin 1-7 (By similarity). Acts specifically as a functional antagonist of AGTR1 (angiotensin-2 type 1 receptor), although it up-regulates AGTR1 receptor levels Positive regulation of AGTR1 levels occurs through activation of the G-proteins GNA11 and GNAQ, and stimulation of the protein kinase C signaling cascade. The antagonist effect on AGTR1 function is probably due to AGTR1 being physically altered by MAS1 |
| Tissue Specificity | This MAS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 284-314 amino acids from the C-terminal region of human MAS1. |
| Cellular Localization | Cell membrane; Multi-pass membrane protein. |
| Entrez Gene | 4142 |
|---|---|
| Nucleotide Accession | NP_002368.1 |
Application
MAS1 Antibody (C-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the MAS1 antibody detected the MAS1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
