Application
MBL2 Antibody (C-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the MBL2 antibody detected the MBL2 protein (arrow).Application
Western blot analysis of MBL2 (arrow) using rabbit polyclonal MBL2 Antibody (C-term) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the MBL2 gene.Application
Confocal immunofluorescent analysis of MBL2 Antibody (C-term)(Cat#AP13736b) with A549 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).Application
MBL2 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MBL2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | MBL2 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MBL2; COLEC1; MBL; Mannose-binding protein C; Collectin-1; MBP1; Mannan-binding protein; Mannose-binding lectin |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIFIHC |
| WB:1:100~500 IF |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | COLEC1 MBL |
|---|---|
| Alternative Names | MBL2 COLEC1 MBL Mannose-binding protein C Collectin-1 MBP1 Mannan-binding protein Mannose-binding lectin |
| Molecular Weight(MW) | 26144 Da |
| Function | Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. May bind DNA |
| Tissue Specificity | Plasma protein produced mainly in the liver. |
| Cellular Localization | Secreted. |
| Entrez Gene | 4153 |
|---|---|
| Nucleotide Accession | NP_000233.1 |
Application
MBL2 Antibody (C-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the MBL2 antibody detected the MBL2 protein (arrow).
Application
Western blot analysis of MBL2 (arrow) using rabbit polyclonal MBL2 Antibody (C-term) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the MBL2 gene.
Application
Confocal immunofluorescent analysis of MBL2 Antibody (C-term)(Cat#AP13736b) with A549 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
Application
MBL2 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MBL2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IF |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
