MCM9 Antibody (C-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the MCM9 antibody detected the MCM9 protein (arrow).
MCM9;C6orf61; MCMDC1; DNA replication licensing factor MCM9; DNA replication licensing factor MCM9; Mini-chromosome maintenance deficient 9; DNA replication licensing factor MCM9; Mini-chromosome maintenance deficient domain-containing protein 1
Key Feature
Clonality
Polyclonal
Isotype
Ig
Host Species
Rabbit
Tested Applications
WB
WB:1:100~500
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
C6orf61 MCMDC1
Alternative Names
MCM9 C6orf61 MCMDC1 DNA replication licensing factor MCM9 DNA replication licensing factor MCM9 Mini-chromosome maintenance deficient 9 DNA replication licensing factor MCM9 Mini-chromosome maintenance deficient domain-containing protein 1
Molecular Weight(MW)
127313 Da
Function
Component of the MCM8-MCM9 complex, a complex involved in homologous recombination repair following DNA interstrand cross-links and plays a key role during gametogenesis. The MCM8- MCM9 complex probably acts as a hexameric helicase downstream of the Fanconi anemia proteins BRCA2 and RAD51 and is required to process aberrant forks into homologous recombination substrates and to orchestrate homologous recombination with resection, fork stabilization and fork restart
Tissue Specificity
This MCM9 Antibody Antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 316-345 amino acids from the C-term region of human MCM9.
Cellular Localization
Nucleus (By similarity). Note=Localizes to nuclear foci and colocalizes with RAD51 (By similarity)
MCM9 Antibody (C-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the MCM9 antibody detected the MCM9 protein (arrow).
Application Notes
WB:1:100~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.