Application
MCRS1 Antibody (N-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the MCRS1 antibody detected the MCRS1 protein (arrow).| Product Name | MCRS1 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MCRS1; INO80Q; MSP58; Microspherule protein 1; 58 kDa microspherule protein; Cell cycle-regulated factor p78; INO80 complex subunit J; MCRS2 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | INO80Q MSP58 |
|---|---|
| Alternative Names | MCRS1 INO80Q MSP58 Microspherule protein 1 58 kDa microspherule protein Cell cycle-regulated factor p78 INO80 complex subunit J MCRS2 |
| Molecular Weight(MW) | 51803 Da |
| Function | Modulates the transcription repressor activity of DAXX by recruiting it to the nucleolus. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. May also be an inhibitor of TERT telomerase activity |
| Tissue Specificity | Detected in testis, and at lower levels in spleen, thymus, prostate, uterus, small intestine, colon and leukocytes |
| Cellular Localization | Nucleus. Nucleus, nucleolus. Note=In microspherules in the nucleolus |
| Entrez Gene | 10445 |
|---|---|
| Nucleotide Accession | NP_006328.2 NP_001012300.1 |
Application
MCRS1 Antibody (N-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the MCRS1 antibody detected the MCRS1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
