Application
MED22 Antibody (N-term) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the MED22 antibody detected the MED22 protein (arrow).| Product Name | MED22 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MED22; SURF5; Mediator of RNA polymerase II transcription subunit 22; Mediator complex subunit 22; Surfeit locus protein 5 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | SURF5 |
|---|---|
| Alternative Names | MED22 SURF5 Mediator of RNA polymerase II transcription subunit 22 Mediator complex subunit 22 Surfeit locus protein 5 |
| Molecular Weight(MW) | 22221 Da |
| Function | Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors |
| Tissue Specificity | This MED22 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 7-36 amino acids from the N-terminal region of human MED22. |
| Cellular Localization | Nucleus (Probable). |
| Entrez Gene | 6837 |
|---|---|
| Nucleotide Accession | NP_598395.1 NP_852468.1 |
Application
MED22 Antibody (N-term) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the MED22 antibody detected the MED22 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
