Application
MEFV Antibody (Center) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the MEFV antibody detected the MEFV protein (arrow).| Product Name | MEFV (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MEFV; MEF; Pyrin; Marenostrin |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | MEF |
|---|---|
| Alternative Names | MEFV MEF Pyrin Marenostrin |
| Molecular Weight(MW) | 86444 Da |
| Function | Probably controls the inflammatory response in myelomonocytic cells at the level of the cytoskeleton organization |
| Tissue Specificity | Expressed in peripheral blood leukocytes, particularly in mature granulocytes and to a lesser extent in monocytes but not in lymphocytes. Detected in spleen, lung and muscle, probably as a result of leukocyte infiltration in these tissues. Not expressed in thymus, prostate, testis, ovary, small intestine, colon, heart, brain, placenta, liver, kidney, pancreas Expression detected in several myeloid leukemic, colon cancer, and prostate cancer cell lines |
| Cellular Localization | Isoform 1: Cytoplasm, cytoskeleton. Note=Associated with microtubules and with the filamentous actin of perinuclear filaments and peripheral lamellar ruffles |
| Entrez Gene | 4210 |
|---|---|
| Nucleotide Accession | NP_000234.1 |
Application
MEFV Antibody (Center) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the MEFV antibody detected the MEFV protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
