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MEKK6 Antibody (C-term)

Catalog Number:OM213571
OM213571
Discount Price
OM213571-100ul
1~2 Week
100ul
OM213571-50ul
50ul
OM213571-20ul
20ul
1~2 Week
Product Profile
Product Name MEKK6 Antibody (C-term)
Antibody Type Primary Antibodies
Antigen Alias MAP3K6; ASK2; MAPKKK6; MEKK6; Mitogen-activated protein kinase kinase kinase 6; Apoptosis signal-regulating kinase 2
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WBIHC
WB:1:100~500 IHC
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms ASK2
MAPKKK6
MEKK6
Alternative Names MAP3K6
ASK2
MAPKKK6
MEKK6
Mitogen-activated protein kinase kinase kinase 6
Apoptosis signal-regulating kinase 2
Molecular Weight(MW) 142596 Da
Function Component of a protein kinase signal transduction cascade. Activates the JNK, but not ERK or p38 kinase pathways
Tissue Specificity This MEKK6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 758~788 amino acids from the C-terminal region of human MEKK6.
Database Links
Entrez Gene 9064
Application

Application

The anti-MEKK6 Pab is used in Western blot to detect MEKK6 in NIH3T3 cell lysate.

Application

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Application Notes WB:1:100~500 IHC
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
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