Application
Western blot analysis of MEMO1 Antibody (N-term) in Jurkat cell line lysates (35ug/lane). MEMO1 (arrow) was detected using the purified Pab.Application
MEMO1 Antibody (N-term) IHC analysis in formalin fixed and paraffin embedded skeletal muscle tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the MEMO1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.Application
MEMO1 Antibody (N-term) flow cytometric analysis of Jurkat cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | MEMO1 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MEMO1; C2orf4; MEMO; NS5ATP7; Protein MEMO1; C21orf19-like protein; Hepatitis C virus NS5A-transactivated protein 7; Mediator of ErbB2-driven cell motility 1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHCFC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | C2orf4 MEMO NS5ATP7 |
|---|---|
| Alternative Names | MEMO1 C2orf4 MEMO NS5ATP7 Protein MEMO1 C21orf19-like protein Hepatitis C virus NS5A-transactivated protein 7 Mediator of ErbB2-driven cell motility 1 |
| Molecular Weight(MW) | 33733 Da |
| Function | May control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton. Mediator of ERBB2 signaling. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity. In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubule capture and stabilization. Is required for breast carcinoma cell migration |
| Tissue Specificity | This MEMO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 63~93 amino acids from the C-terminal region of human MEMO1. |
| Entrez Gene | 51072 |
|---|
Application
Western blot analysis of MEMO1 Antibody (N-term) in Jurkat cell line lysates (35ug/lane). MEMO1 (arrow) was detected using the purified Pab.
Application
MEMO1 Antibody (N-term) IHC analysis in formalin fixed and paraffin embedded skeletal muscle tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the MEMO1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Application
MEMO1 Antibody (N-term) flow cytometric analysis of Jurkat cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
