Application
MESP2 Antibody (N-term) western blot analysis in mouse liver tissue lysates (15ug/lane).This demonstrates the MESP2 antibody detected MESP2 protein (arrow).Application
MESP2 Antibody (N-term) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | MESP2 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MESP2; BHLHC6; SCDO2; Mesoderm posterior protein 2; Class C basic helix-loop-helix protein 6 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBFC |
| WB:1:100~500 FC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | BHLHC6 SCDO2 |
|---|---|
| Alternative Names | MESP2 BHLHC6 SCDO2 Mesoderm posterior protein 2 Class C basic helix-loop-helix protein 6 |
| Molecular Weight(MW) | 41760 Da |
| Function | Transcription factor with important role in somitogenesis. Defines the rostrocaudal patterning of the somite by participating in distinct Notch pathways. Regulates also the FGF signaling pathway. Specifies the rostral half of the somites Generates rostro-caudal polarity of somites by down-regulating in the presumptive rostral domain DLL1, a Notch ligand. Participates in the segment border formation by activating in the anterior presomitic mesoderm LFNG, a negative regulator of DLL1-Notch signaling. Acts as a strong suppressor of Notch activity. Together with MESP1 is involved in the epithelialization of somitic mesoderm and in the development of cardiac mesoderm |
| Tissue Specificity | This MESP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 72-101 amino acids from the N-terminal region of human MESP2. |
| Cellular Localization | Nucleus (By similarity). |
| Entrez Gene | 145873 |
|---|---|
| Nucleotide Accession | NP_001035047.1 |
Application
MESP2 Antibody (N-term) western blot analysis in mouse liver tissue lysates (15ug/lane).This demonstrates the MESP2 antibody detected MESP2 protein (arrow).
Application
MESP2 Antibody (N-term) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 FC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
