Application
MESDC2 Antibody (C-term)immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MESDC2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.Application
MESDC2 Antibody (C-term) western blot analysis in Hela,293,HepG2 cell line lysates (35ug/lane).This demonstrates the MESDC2 antibody detected the MESDC2 protein (arrow).Application
Confocal immunofluorescent analysis of MESDC2 Antibody (C-term)(Cat#AP11638b) with 293 cell followed by Alexa Fluor? 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).| Product Name | MESDC2 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MESDC2; KIAA0081; MESD; LDLR chaperone MESD; Mesoderm development candidate 2; Mesoderm development protein; Renal carcinoma antigen NY-REN-61 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | IHCWBIF |
| IHC:1:10~50 WB |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | KIAA0081 MESD |
|---|---|
| Alternative Names | MESDC2 KIAA0081 MESD LDLR chaperone MESD Mesoderm development candidate 2 Mesoderm development protein Renal carcinoma antigen NY-REN-61 |
| Molecular Weight(MW) | 26077 Da |
| Function | Chaperone specifically assisting the folding of beta- propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs). Acts as a modulator of the Wnt pathway through chaperoning the coreceptors of the canonical Wnt pathway, LRP5 and LRP6, to the plasma membrane. Essential for specification of embryonic polarity and mesoderm induction |
| Tissue Specificity | This MESDC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 203-234 amino acids from the C-terminal region of human MESDC2. |
| Cellular Localization | Endoplasmic reticulum. |
| Entrez Gene | 23184 |
|---|---|
| Nucleotide Accession | NP_055969.1 |
Application
MESDC2 Antibody (C-term)immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MESDC2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Application
MESDC2 Antibody (C-term) western blot analysis in Hela,293,HepG2 cell line lysates (35ug/lane).This demonstrates the MESDC2 antibody detected the MESDC2 protein (arrow).
Application
Confocal immunofluorescent analysis of MESDC2 Antibody (C-term)(Cat#AP11638b) with 293 cell followed by Alexa Fluor? 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).| Application Notes | IHC:1:10~50 WB |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
