Application
MFN1 Antibody (Center) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the MFN1 antibody detected the MFN1 protein (arrow).| Product Name | MFN1 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MFN1; Mitofusin-1; Fzo homolog; Transmembrane GTPase MFN1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | MFN1 Mitofusin-1 Fzo homolog Transmembrane GTPase MFN1 |
|---|---|
| Molecular Weight(MW) | 84100 Da |
| Function | Essential transmembrane GTPase, which mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission. MFN1 acts independently of the cytoskeleton. Overexpression induces the formation of mitochondrial networks |
| Tissue Specificity | Ubiquitous. Expressed at slightly higher level in kidney and heart. Isoform 2 may be overexpressed in some tumors, such as lung cancers |
| Cellular Localization | Mitochondrion outer membrane; Multi-pass membrane protein (Probable) |
| Entrez Gene | 55669 |
|---|---|
| Nucleotide Accession | NP_284941.2 |
Application
MFN1 Antibody (Center) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the MFN1 antibody detected the MFN1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
