Application
MGAT4C Antibody (C-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the MGAT4C antibody detected the MGAT4C protein (arrow).Application
MGAT4C Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MGAT4C Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | MGAT4C Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MGAT4C; Alpha-1, 3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C; N-acetylglucosaminyltransferase IV homolog; N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVc; UDP-N-acetylglucosamine: alpha-1, 3-D-mannoside beta |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | MGAT4C Alpha-1 3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C N-acetylglucosaminyltransferase IV homolog N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVc UDP-N-acetylglucosamine: alpha-1 3-D-mannoside beta |
|---|---|
| Molecular Weight(MW) | 56061 Da |
| Function | Glycosyltransferase that participates in the transfer of N-acetylglucosamine (GlcNAc) to the core mannose residues of N- linked glycans. Catalyzes the formation of the GlcNAcbeta1-4 branch on the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans. Essential for the production of tri- and tetra-antennary N-linked sugar chains (By similarity). Does not catalyze the transfer of GlcNAc to the Manalpha1-6 arm to form GlcNAcBeta1-4Manalpha1-6 linkage ('GnT-VI' activity) |
| Tissue Specificity | Expressed in heart, adrenal gland, testis, liver, brain and fetal brain. Not expressed in pancreas |
| Cellular Localization | Golgi apparatus membrane; Single-pass type II membrane protein (By similarity) |
| Entrez Gene | 25834 |
|---|---|
| Nucleotide Accession | NP_037376.2 |
Application
MGAT4C Antibody (C-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the MGAT4C antibody detected the MGAT4C protein (arrow).
Application
MGAT4C Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MGAT4C Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
