Application
Western blot analysis of MIIP Antibody (C-term) in ZR-75-1 cell line lysates (35ug/lane).MIIP (arrow) was detected using the purified Pab.| Product Name | MIIP Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MIIP; IIP45; Migration and invasion-inhibitory protein; IGFBP2-binding protein; Invasion-inhibitory protein 45 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | IIP45 |
|---|---|
| Alternative Names | MIIP IIP45 Migration and invasion-inhibitory protein IGFBP2-binding protein Invasion-inhibitory protein 45 |
| Molecular Weight(MW) | 42824 Da |
| Function | Inhibits glioma cells invasion and down-regulates adhesion- and motility-associated genes such as NFKB2 and ICAM1 Exhibits opposing effects to IGFBP2 on cell invasion |
| Tissue Specificity | Ubiquitous. Isoform 1 is expressed in brain but underexpressed in glioma tissues, at protein level. Isoform 2 is not detected in normal organs, but is expressed in gliomas with increasing levels with glioma progression. On the contrary, at protein level, isoform 2 is not detected in gliomas, suggesting that this isoform is unstable in glioma cells |
| Entrez Gene | 60672 |
|---|
Application
Western blot analysis of MIIP Antibody (C-term) in ZR-75-1 cell line lysates (35ug/lane).MIIP (arrow) was detected using the purified Pab.| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
