Application
MIER1 Antibody (Center) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the MIER1 antibody detected the MIER1 protein (arrow).| Product Name | MIER1 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MIER1; KIAA1610; Mesoderm induction early response protein 1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | KIAA1610 |
|---|---|
| Alternative Names | MIER1 KIAA1610 Mesoderm induction early response protein 1 |
| Molecular Weight(MW) | 57983 Da |
| Function | Transcriptional repressor regulating the expression of a number of genes including SP1 target genes. Probably functions through recruitment of HDAC1 a histone deacetylase involved in chromatin silencing |
| Tissue Specificity | Ubiquitously expressed, but at very low levels. However, consistent level of expression are observed in heart, testis, thyroid, ovary and adrenal gland. Transcripts are up-regulated in breast carcinoma cell lines and tumor |
| Cellular Localization | Isoform 1: Nucleus. Isoform 3: Nucleus. Isoform 5: Cytoplasm. |
| Entrez Gene | 57708 |
|---|---|
| Nucleotide Accession | NP_001071169.1 |
Application
MIER1 Antibody (Center) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the MIER1 antibody detected the MIER1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
