Application
A. Western blot of anti-MIP1 beta (N-term) RabMAb (Cat. #AJ1481b).| Product Name | MIP-1 beta/CCL4 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CCL4, LAG1, MIP1B, SCYA4, MIP-1-beta(3-69), HC21;G-26 T-lymphocyte-secreted protein |
| Clonality | Monoclonal |
|---|---|
| Clone Number | EP521Y |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:5000~10000 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | LAG1 MIP1B SCYA4 |
|---|---|
| Alternative Names | CCL4 LAG1 MIP1B SCYA4 MIP-1-beta(3-69) HC21 G-26 T-lymphocyte-secreted protein |
| Molecular Weight(MW) | 10212 Da |
| Function | Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5- mediated entry of HIV-1 in T-cells. MIP-1-beta(3-69) is also a ligand for CCR1 and CCR2 isoform B |
| Tissue Specificity | A synthetic peptide corresponding to residues in the N-terminus of human MIP-1 beta/CCL4 was used as an immunogen. |
| Cellular Localization | Secreted. |
| Entrez Gene | 9560 |
|---|
Application
A. Western blot of anti-MIP1 beta (N-term) RabMAb (Cat. #AJ1481b).| Application Notes | WB:1:5000~10000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
