MIXL1 Antibody (Center) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the MIXL1 antibody detected the MIXL1 protein (arrow).
MIXL1; MIXL; Homeobox protein MIXL1; Homeodomain protein MIX; MIX1 homeobox-like protein 1; Mix.1 homeobox-like protein
Key Feature
Clonality
Polyclonal
Isotype
Ig
Host Species
Rabbit
Tested Applications
WB
WB:1:100~500
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
MIXL
Alternative Names
MIXL1 MIXL Homeobox protein MIXL1 Homeodomain protein MIX MIX1 homeobox-like protein 1 Mix.1 homeobox-like protein
Molecular Weight(MW)
24659 Da
Function
Transcription factor that play a central role in proper axial mesendoderm morphogenesis and endoderm formation. Required for efficient differentiation of cells from the primitive streak stage to blood, by acting early in the recruitment and/or expansion of mesodermal progenitors to the hemangioblastic and hematopoietic lineages. Also involved in the morphogenesis of the heart and the gut during embryogenesis. Acts as a negative regulator of brachyury expression (By similarity)
Tissue Specificity
Restricted to progenitors and secondary lymph tissues. In normal hematopoiesis, it is restricted to immature B- and T-lymphoid cells. Present in differentiating embryonic stem cells (at protein level)
MIXL1 Antibody (Center) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the MIXL1 antibody detected the MIXL1 protein (arrow).
Application Notes
WB:1:100~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.