Application
MKKS Antibody (C-term) western blot analysis in U251 cell line lysates (35ug/lane).This demonstrates the MKKS antibody detected the MKKS protein (arrow).| Product Name | MKKS Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MKKS; BBS6; McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin; Bardet-Biedl syndrome 6 protein |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | BBS6 |
|---|---|
| Alternative Names | MKKS BBS6 McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin Bardet-Biedl syndrome 6 protein |
| Molecular Weight(MW) | 62342 Da |
| Function | Probable molecular chaperone. Assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. May play a role in protein processing in limb, cardiac and reproductive system development. May play a role in cytokinesis |
| Tissue Specificity | Widely expressed in adult and fetal tissues. |
| Cellular Localization | Cytoplasm, cytoskeleton, centrosome. Cytoplasm, cytosol. Note=The majority of the protein resides within the pericentriolar material (PCM), a proteinaceous tube surrounding centrioles. During interphase, the protein is confined to the lateral surfaces of the PCM but during mitosis it relocalizes throughout the PCM and is found at the intercellular bridge. The MKSS protein is highly mobile and rapidly shuttles between the cytosol and centrosome |
| Entrez Gene | 8195 |
|---|---|
| Nucleotide Accession | NP_740754.1 NP_061336.1 |
Application
MKKS Antibody (C-term) western blot analysis in U251 cell line lysates (35ug/lane).This demonstrates the MKKS antibody detected the MKKS protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
