Application
MKL1 Antibody (Center) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the MKL1 antibody detected the MKL1 protein (arrow).| Product Name | MKL1 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MKL1; KIAA1438; MAL; MKL/myocardin-like protein 1; Megakaryoblastic leukemia 1 protein; Megakaryocytic acute leukemia protein; Myocardin-related transcription factor A |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | KIAA1438 MAL |
|---|---|
| Alternative Names | MKL1 KIAA1438 MAL MKL/myocardin-like protein 1 Megakaryoblastic leukemia 1 protein Megakaryocytic acute leukemia protein Myocardin-related transcription factor A |
| Molecular Weight(MW) | 98919 Da |
| Function | Transcriptional coactivator of serum response factor (SRF) with the potential to modulate SRF target genes. Suppresses TNF-induced cell death by inhibiting activation of caspases; its transcriptional activity is indispensable for the antiapoptotic function. It may up-regulate antiapoptotic molecules, which in turn inhibit caspase activation (By similarity) |
| Tissue Specificity | Ubiquitously expressed, has been detected in lung, placenta, small intestine, liver, kidney, spleen, thymus, colon, muscle, heart and brain |
| Cellular Localization | Cytoplasm (By similarity). Nucleus (By similarity). Note=Binding to globular actin is required to maintain cytoplasmic localization (By similarity) |
| Entrez Gene | 57591 |
|---|---|
| Nucleotide Accession | NP_065882.1 |
Application
MKL1 Antibody (Center) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the MKL1 antibody detected the MKL1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
