Application
MMEL1 Antibody (N-term) western blot analysis in human Uterus tissue lysates (35ug/lane).This demonstrates the MMEL1 antibody detected the MMEL1 protein (arrow).| Product Name | MMEL1 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MMEL1; MELL1; MMEL2; NEP2; Membrane metallo-endopeptidase-like 1; Membrane metallo-endopeptidase-like 2; NEP2(m); Neprilysin II; Neprilysin-2; Membrane metallo-endopeptidase-like 1, soluble form; Neprilysin-2 secreted |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | MELL1 MMEL2 NEP2 |
|---|---|
| Alternative Names | MMEL1 MELL1 MMEL2 NEP2 Membrane metallo-endopeptidase-like 1 Membrane metallo-endopeptidase-like 2 NEP2(m) Neprilysin II Neprilysin-2 Membrane metallo-endopeptidase-like 1 soluble form Neprilysin-2 secreted |
| Molecular Weight(MW) | 89367 Da |
| Function | Metalloprotease involved in sperm function, possibly by modulating the processes of fertilization and early embryonic development. Degrades a broad variety of small peptides with a preference for peptides shorter than 3 kDa containing neutral bulky aliphatic or aromatic amino acid residues. Shares the same substrate specificity with MME and cleaves peptides at the same amide bond (By similarity) |
| Tissue Specificity | Predominantly expressed in testis. Weakly expressed in brain, kidney and heart |
| Cellular Localization | Membrane; Single-pass type II membrane protein. Secreted. Note=A secreted form produced by proteollytic cleavage also exists (By similarity) |
| Entrez Gene | 79258 |
|---|---|
| Nucleotide Accession | NP_258428.2 |
Application
MMEL1 Antibody (N-term) western blot analysis in human Uterus tissue lysates (35ug/lane).This demonstrates the MMEL1 antibody detected the MMEL1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
