Application
Western blot analysis of MMP24 Antibody (Center) in HL60 cell line lysates (35ug/lane). MMP24 (arrow) was detected using the purified Pab.Application
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.| Product Name | MMP24 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MMP24; MT5MMP; Matrix metalloproteinase-24; Membrane-type matrix metalloproteinase 5; Membrane-type-5 matrix metalloproteinase; Processed matrix metalloproteinase-24 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | MT5MMP |
|---|---|
| Alternative Names | MMP24 MT5MMP Matrix metalloproteinase-24 Membrane-type matrix metalloproteinase 5 Membrane-type-5 matrix metalloproteinase Processed matrix metalloproteinase-24 |
| Molecular Weight(MW) | 73231 Da |
| Function | Activates progelatinase A. May also be a proteoglycanase involved in degradation of proteoglycans, such as dermatan sulfate and chondroitin sulfate proteoglycans. Cleaves partially fibronectin, but not collagen type I, nor laminin (By similarity) |
| Tissue Specificity | Predominantly expressed in brain, kidney, pancreas and lung. Overexpressed in a series of brain tumors, including astrocytomas and glioblastomas |
| Cellular Localization | Cell membrane; Single-pass type I membrane protein; Extracellular side (By similarity) |
Application
Western blot analysis of MMP24 Antibody (Center) in HL60 cell line lysates (35ug/lane). MMP24 (arrow) was detected using the purified Pab.
Application
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
