Application
MMRN1 Antibody (N-term) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the MMRN1 antibody detected the MMRN1 protein (arrow).| Product Name | MMRN1 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MMRN1; ECM; EMILIN4; GPIA*; MMRN; Multimerin-1; EMILIN-4; Elastin microfibril interface located protein 4; Endothelial cell multimerin; Platelet glycoprotein Ia*; 155 kDa platelet multimerin |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | ECM EMILIN4 GPIA* MMRN |
|---|---|
| Alternative Names | MMRN1 ECM EMILIN4 GPIA* MMRN Multimerin-1 EMILIN-4 Elastin microfibril interface located protein 4 Endothelial cell multimerin Platelet glycoprotein Ia* 155 kDa platelet multimerin |
| Molecular Weight(MW) | 138110 Da |
| Function | Carrier protein for platelet (but not plasma) factor V/Va. Plays a role in the storage and stabilization of factor V in platelets. Upon release following platelet activation, may limit platelet and plasma factor Va-dependent thrombin generation Ligand for integrin alpha-IIb/beta-3 and integrin alpha-V/beta-3 on activated platelets, and may function as an extracellular matrix or adhesive protein |
| Tissue Specificity | Synthesized by endothelial cells and megakaryocytes. Stored in platelet alpha granules and endothelial cell Weibel-Palade bodies, following activation of these cells, it is released and attached to megakaryocytes, platelets, endothelium and subendothelium of blood vessels. Not found in plasma. Found in vascular tissues such as placenta, lung, and liver |
| Cellular Localization | Secreted (Potential). |
| Entrez Gene | 22915 |
|---|---|
| Nucleotide Accession | NP_031377.2 |
Application
MMRN1 Antibody (N-term) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the MMRN1 antibody detected the MMRN1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
