Application
MORF4L2 Antibody (C-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the MORF4L2 antibody detected the MORF4L2 protein (arrow).| Product Name | MORF4L2 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MORF4L2; KIAA0026; MRGX; Mortality factor 4-like protein 2; MORF-related gene X protein; Protein MSL3-2; Transcription factor-like protein MRGX |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | KIAA0026 MRGX |
|---|---|
| Alternative Names | MORF4L2 KIAA0026 MRGX Mortality factor 4-like protein 2 MORF-related gene X protein Protein MSL3-2 Transcription factor-like protein MRGX |
| Molecular Weight(MW) | 32308 Da |
| Function | Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also component of the MSIN3A complex which acts to repress transcription by deacetylation of nucleosomal histones |
| Tissue Specificity | This MORF4L2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 258-288 amino acids from the C-terminal region of human MORF4L2. |
| Cellular Localization | Nucleus. |
| Entrez Gene | 9643 |
|---|---|
| Nucleotide Accession | NP_001135901.1 NP_001135891.1 NP_001135898.1 |
Application
MORF4L2 Antibody (C-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the MORF4L2 antibody detected the MORF4L2 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
