Application
Western blot analysis of MORG1 Antibody (Center) in K562 cell line lysates (35ug/lane). MORG1 (arrow) was detected using the purified Pab.| Product Name | MORG1 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | WDR83; MORG1; WD repeat domain-containing protein 83; Mitogen-activated protein kinase organizer 1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | MORG1 |
|---|---|
| Alternative Names | WDR83 MORG1 WD repeat domain-containing protein 83 Mitogen-activated protein kinase organizer 1 |
| Molecular Weight(MW) | 34343 Da |
| Function | Molecular scaffold protein for various multimeric protein complexes. Acts as a module in the assembly of a multicomponent scaffold for the ERK pathway, linking ERK responses to specific agonists. At low concentrations it enhances ERK activation, whereas high concentrations lead to the inhibition of ERK activation. Also involved in response to hypoxia by acting as a negative regulator of HIF1A/HIF-1-alpha via its interaction with EGLN3/PHD3. May promote degradation of HIF1A. May act by recruiting signaling complexes to a specific upstream activator (By similarity). May also be involved in pre-mRNA splicing |
| Tissue Specificity | This MORG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Central region of human MORG1. |
| Cellular Localization | Cytoplasm (By similarity). Nucleus (By similarity). Note=Predominantly cytoplasmic (By similarity) Partially nuclear (By similarity) |
| Entrez Gene | 84292 |
|---|
Application
Western blot analysis of MORG1 Antibody (Center) in K562 cell line lysates (35ug/lane). MORG1 (arrow) was detected using the purified Pab.| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
