Application
Western blot analysis of MOSC1 Antibody (Center) in HepG2 cell line lysates (35ug/lane). MOSC1 (arrow) was detected using the purified Pab.Application
MOSC1 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the MOSC1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | MOSC1 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MARC1; MOSC1; MOSC domain-containing protein 1, mitochondrial; Mitochondrial amidoxime reducing component 1; Moco sulfurase C-terminal domain-containing protein 1; Molybdenum cofactor sulfurase C-terminal domain-containing protein 1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | MOSC1 |
|---|---|
| Alternative Names | MARC1 MOSC1 MOSC domain-containing protein 1 mitochondrial Mitochondrial amidoxime reducing component 1 Moco sulfurase C-terminal domain-containing protein 1 Molybdenum cofactor sulfurase C-terminal domain-containing protein 1 |
| Molecular Weight(MW) | 37499 Da |
| Function | As a component of an N-hydroxylated prodrug-converting complex required to reduce N-hydroxylated prodrugs, such as benzamidoxime. Also able to reduce N(omega)-hydroxy-L-arginine (NOHA) and N(omega)-hydroxy-N(delta)-methyl-L-arginine (NHAM) into L-arginine and N(delta)-methyl-L-arginine, respectively |
| Tissue Specificity | This MOSC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 182~212 amino acids from the Central region of human MOSC1. |
| Cellular Localization | Mitochondrion outer membrane; Single-pass type II membrane protein. Note=Mitochondrial import is mediated by AA 1-40 and requires ATP |
| Entrez Gene | 64757 |
|---|
Application
Western blot analysis of MOSC1 Antibody (Center) in HepG2 cell line lysates (35ug/lane). MOSC1 (arrow) was detected using the purified Pab.
Application
MOSC1 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the MOSC1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
