Application
Mouse Acvr1 Antibody (Center) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the Acvr1 antibody detected the Acvr1 protein (arrow).Application
Western blot analysis of Acvr1 (arrow) using rabbit polyclonal Mouse Acvr1 Antibody (Center) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the Acvr1 gene.Application
Mouse Acvr1 Antibody (Center) western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the Acvr1 antibody detected the Acvr1 protein (arrow).Application
Mouse Acvr1 Antibody (Center) (AP13796c)immunohistochemistry analysis in formalin fixed and paraffin embedded mouse skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of Mouse Acvr1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | Acvr1 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Acvr1; Acvrlk2; Tgfb1; Activin receptor type-1; Activin receptor type I; Serine/threonine-protein kinase receptor R1; TGF-B superfamily receptor type I; TSK-7L |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | Acvrlk2 Tgfb1 |
|---|---|
| Alternative Names | Acvr1 Acvrlk2 Tgfb1 Activin receptor type-1 Activin receptor type I Serine/threonine-protein kinase receptor R1 TGF-B superfamily receptor type I TSK-7L |
| Molecular Weight(MW) | 57226 Da |
| Function | On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin. May be involved in left-right pattern formation during embryogenesis |
| Tissue Specificity | Expressed in normal parenchymal cells, endothelial cells, fibroblasts and tumor-derived epithelial cells |
| Cellular Localization | Membrane; Single-pass type I membrane protein |
| Entrez Gene | 11477 |
|---|---|
| Nucleotide Accession | NP_031420.2 NP_001103675.1 |
Application
Mouse Acvr1 Antibody (Center) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the Acvr1 antibody detected the Acvr1 protein (arrow).
Application
Western blot analysis of Acvr1 (arrow) using rabbit polyclonal Mouse Acvr1 Antibody (Center) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the Acvr1 gene.
Application
Mouse Acvr1 Antibody (Center) western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the Acvr1 antibody detected the Acvr1 protein (arrow).
Application
Mouse Acvr1 Antibody (Center) (AP13796c)immunohistochemistry analysis in formalin fixed and paraffin embedded mouse skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of Mouse Acvr1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
