Application
Mouse Acvr1c Antibody (C-term) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the Acvr1c antibody detected the Acvr1c protein (arrow).| Product Name | Acvr1c Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Acvr1c; Alk7; Activin receptor type-1C; Activin receptor type IC; Activin receptor-like kinase 7 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | Alk7 |
|---|---|
| Alternative Names | Acvr1c Alk7 Activin receptor type-1C Activin receptor type IC Activin receptor-like kinase 7 |
| Molecular Weight(MW) | 54700 Da |
| Function | Serine/threonine protein kinase which forms a receptor complex on ligand binding. The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3. Receptor for activin AB, activin B and NODAL. Plays a role in cell differentiation, growth arrest and apoptosis |
| Tissue Specificity | Expressed in interdigital regions in developing limb buds |
| Cellular Localization | Membrane; Single-pass type I membrane protein (By similarity) |
| Entrez Gene | 269275 |
|---|---|
| Nucleotide Accession | NP_001104500.1 |
Application
Mouse Acvr1c Antibody (C-term) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the Acvr1c antibody detected the Acvr1c protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
