Application
Mouse Acvrl1 Antibody (C-term) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the Acvrl1 antibody detected the Acvrl1 protein (arrow).Application
Mouse Acvrl1 Antibody (C-term) (AP14702b)immunohistochemistry analysis in formalin fixed and paraffin embedded mouse brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of Mouse Acvrl1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | Acvrl1 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Acvrl1; Acvrlk1; Alk-1; Serine/threonine-protein kinase receptor R3; Activin receptor-like kinase 1; TGF-B superfamily receptor type I |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | Acvrlk1 Alk-1 |
|---|---|
| Alternative Names | Acvrl1 Acvrlk1 Alk-1 Serine/threonine-protein kinase receptor R3 Activin receptor-like kinase 1 TGF-B superfamily receptor type I |
| Molecular Weight(MW) | 56519 Da |
| Function | Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. May bind activin as well |
| Tissue Specificity | This Mouse Acvrl1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 470-498 amino acids from the C-terminal region of Mouse Acvrl1. |
| Cellular Localization | Membrane; Single-pass type I membrane protein |
| Entrez Gene | 11482 |
|---|---|
| Nucleotide Accession | NP_033742.2 |
Application
Mouse Acvrl1 Antibody (C-term) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the Acvrl1 antibody detected the Acvrl1 protein (arrow).
Application
Mouse Acvrl1 Antibody (C-term) (AP14702b)immunohistochemistry analysis in formalin fixed and paraffin embedded mouse brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of Mouse Acvrl1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
