Application
Mouse Bmpr2 Antibody (C-term) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the Bmpr2 antibody detected the Bmpr2 protein (arrow).Application
Mouse Bmpr2 Antibody (C-term) western blot analysis in human uterine tumor cell line lysates (35ug/lane).This demonstrates the Bmpr2 antibody detected the Bmpr2 protein (arrow).| Product Name | Bmpr2 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Bmpr2; Bone morphogenetic protein receptor type-2; BRK-3; Bone morphogenetic protein receptor type II |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | Bmpr2 Bone morphogenetic protein receptor type-2 BRK-3 Bone morphogenetic protein receptor type II |
|---|---|
| Molecular Weight(MW) | 115020 Da |
| Function | On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Binds to BMP-7, BMP-2 and, less efficiently, BMP-4. Binding is weak but enhanced by the presence of type I receptors for BMPs |
| Tissue Specificity | This Mouse Bmpr2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 949-978 amino acids from the C-terminal region of mouse Bmpr2. |
| Cellular Localization | Membrane; Single-pass type I membrane protein |
| Entrez Gene | 12168 |
|---|---|
| Nucleotide Accession | NP_031587.1 |
Application
Mouse Bmpr2 Antibody (C-term) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the Bmpr2 antibody detected the Bmpr2 protein (arrow).
Application
Mouse Bmpr2 Antibody (C-term) western blot analysis in human uterine tumor cell line lysates (35ug/lane).This demonstrates the Bmpr2 antibody detected the Bmpr2 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
