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Cask Antibody (N-term)

Catalog Number:OM214020
OM214020
Discount Price
OM214020-100ul
1~2 Week
100ul
OM214020-50ul
50ul
OM214020-20ul
20ul
1~2 Week
Product Profile
Product Name Cask Antibody (N-term)
Antibody Type Primary Antibodies
Antigen Alias Cask; Peripheral plasma membrane protein CASK; Calcium/calmodulin-dependent serine protein kinase
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WBIHC
WB:1:100~500 IHC
Species Reactivity Human
Concentration 1mg/ml
Target Information
Alternative Names Cask
Peripheral plasma membrane protein CASK
Calcium/calmodulin-dependent serine protein kinase
Molecular Weight(MW) 105109 Da
Function Multidomain scaffolding protein with a role in synaptic transmembrane protein anchoring and ion channel trafficking Contributes to neural development and regulation of gene expression via interaction with the transcription factor TRB1 Binds to cell-surface proteins, including amyloid precursor protein, neurexins, and syndecans. May mediate a link between the extracellular matrix and the actin cytoskeleton via its interaction with syndecan and with the actin/spectrin-binding protein 4.1
Tissue Specificity This Mouse Cask antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 212-241 amino acids from the N-terminal region of Mouse Cask.
Cellular Localization Nucleus (By similarity). Cytoplasm (By similarity). Cell membrane; Peripheral membrane protein (By similarity)
Database Links
Entrez Gene 12361
Nucleotide Accession NP_033936.2
Application

Application

Mouse Cask Antibody (N-term) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the Cask antibody detected the Cask protein (arrow).

Application

Mouse Cask Antibody (N-term) (AP14818a)immunohistochemistry analysis in formalin fixed and paraffin embedded mouse cerebellum tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of Mouse Cask Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Application Notes WB:1:100~500 IHC
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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