Application
Mouse Cdk16 Antibody (N-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the Cdk16 antibody detected the Cdk16 protein (arrow).Application
Mouse Cdk16 Antibody (N-term) western blot analysis in mouse Neuro-2a cell line lysates (35ug/lane).This demonstrates the Cdk16 antibody detected the Cdk16 protein (arrow).Application
Mouse Cdk16 Antibody (N-term) flow cytometric analysis of Neuro-2a cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis.| Product Name | Cdk16 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Cdk16; Crk5; Pctk1; Cyclin-dependent kinase 16; CRK5; Cell division protein kinase 16; PCTAIRE-motif protein kinase 1; Serine/threonine-protein kinase PCTAIRE-1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBFC |
| WB:1:100~500 FC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | Crk5 Pctaire1 Pctk1 |
|---|---|
| Alternative Names | Cdk16 Crk5 Pctk1 Cyclin-dependent kinase 16 CRK5 Cell division protein kinase 16 PCTAIRE-motif protein kinase 1 Serine/threonine-protein kinase PCTAIRE-1 |
| Molecular Weight(MW) | 55914 Da |
| Function | Protein kinase that plays a role in vesicle-mediated transport processes and exocytosis. Can phosphorylate CCNY at 'Ser-336' (in vitro) (By similarity). Plays a role in the regulation of insulin secretion in response to changes in blood glucose levels. Regulates GH1 release by brain neurons Phosphorylates NSF, and thereby regulates NSF oligomerization Required for normal spermatogenesis. Regulates neuron differentiation and dendrite development |
| Tissue Specificity | Highly expressed in testis and brain, and detected at lower levels in heart, skeletal muscle, adipose tissue, lung, spleen and pancreas (at protein level). Ubiquitous with highest levels in testis and brain, with longer form predominant in all tissues except the testis |
| Cellular Localization | Cytoplasm (By similarity). Cytoplasmic vesicle, secretory vesicle. Cell junction, synapse, synaptosome Note=Colocalizes with insulin in pancreas islets (By similarity) |
| Entrez Gene | 18555 |
|---|---|
| Nucleotide Accession | NP_035179.1 |
Application
Mouse Cdk16 Antibody (N-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the Cdk16 antibody detected the Cdk16 protein (arrow).
Application
Mouse Cdk16 Antibody (N-term) western blot analysis in mouse Neuro-2a cell line lysates (35ug/lane).This demonstrates the Cdk16 antibody detected the Cdk16 protein (arrow).
Application
Mouse Cdk16 Antibody (N-term) flow cytometric analysis of Neuro-2a cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 FC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
