Application
Mouse Cdk3 Antibody (C-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the Cdk3 antibody detected the Cdk3 protein (arrow).Application
Western blot analysis of Cdk3 (arrow) using rabbit polyclonal Mouse Cdk3 Antibody (C-term) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the Cdk3 gene.| Product Name | Cdk3 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Cdk3; Cdkn3; Cyclin-dependent kinase 3; Cell division protein kinase 3 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | Cdkn3 |
|---|---|
| Alternative Names | Cdk3 Cdkn3 Cyclin-dependent kinase 3 Cell division protein kinase 3 |
| Molecular Weight(MW) | 33888 Da |
| Function | Serine/threonine-protein kinase that plays a critical role in the control of the eukaryotic cell cycle; involved in G0- G1 and G1-S cell cycle transitions. Interacts with CCNC/cyclin-C during interphase. Phosphorylates histone H1, ATF1, RB1 and CABLES1. ATF1 phosphorylation triggers ATF1 transactivation and transcriptional activities, and promotes cell proliferation and transformation. CDK3/cyclin-C mediated RB1 phosphorylation is required for G0-G1 transition. Promotes G1-S transition probably by contributing to the activation of E2F1, E2F2 and E2F3 in a RB1- independent manner |
| Tissue Specificity | This Mouse Cdk3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 248-277 amino acids from the C-terminal region of Mouse Cdk3. |
Application
Mouse Cdk3 Antibody (C-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the Cdk3 antibody detected the Cdk3 protein (arrow).
Application
Western blot analysis of Cdk3 (arrow) using rabbit polyclonal Mouse Cdk3 Antibody (C-term) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the Cdk3 gene.| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
