Application
Mouse Clk3 Antibody (N-term) western blot analysis in mouse testis tissue lysates (35ug/lane).This demonstrates the Clk3 antibody detected the Clk3 protein (arrow).| Product Name | Clk3 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Clk3; Dual specificity protein kinase CLK3; CDC-like kinase 3 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | Clk3 Dual specificity protein kinase CLK3 CDC-like kinase 3 |
|---|---|
| Molecular Weight(MW) | 73798 Da |
| Function | Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex. May be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing and can cause redistribution of SR proteins from speckles to a diffuse nucleoplasmic distribution Phosphorylates SRSF1 and SRSF3. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells |
| Tissue Specificity | Present at high levels in testis and ovary. In testis, expression is restricted to elongated, maturing spermatozoa. Also present in spleen, brain, lung and liver (at protein level) |
| Cellular Localization | Nucleus. Cytoplasm. Cytoplasmic vesicle, secretory vesicle, acrosome |
| Entrez Gene | 102414 |
|---|---|
| Nucleotide Accession | NP_031739.3 |
Application
Mouse Clk3 Antibody (N-term) western blot analysis in mouse testis tissue lysates (35ug/lane).This demonstrates the Clk3 antibody detected the Clk3 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
