Application
Mouse Clk4 Antibody (N-term) western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the Clk4 antibody detected the Clk4 protein (arrow).| Product Name | Clk4 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Clk4; Dual specificity protein kinase CLK4; CDC-like kinase 4 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | Clk4 Dual specificity protein kinase CLK4 CDC-like kinase 4 |
|---|---|
| Molecular Weight(MW) | 57345 Da |
| Function | Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex and may be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing. Phosphorylates SRSF1 and SRSF3 Required for the regulation of alternative splicing of MAPT/TAU Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells |
| Tissue Specificity | Expressed in the hippocampus, the cerebellum and the olfactory bulb |
| Cellular Localization | Nucleus. |
| Entrez Gene | 12750 |
|---|---|
| Nucleotide Accession | NP_031740.1 |
Application
Mouse Clk4 Antibody (N-term) western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the Clk4 antibody detected the Clk4 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
