Application
Mouse Dapk2 Antibody (N-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the Dapk2 antibody detected the Dapk2 protein (arrow).Application
Western blot analysis of Dapk2 (arrow) using rabbit polyclonal Mouse Dapk2 Antibody (N-term) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the Dapk2 gene.| Product Name | Dapk2 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Dapk2; Death-associated protein kinase 2; DAP-kinase-related protein 1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | Dapk2 Death-associated protein kinase 2 DAP-kinase-related protein 1 |
|---|---|
| Molecular Weight(MW) | 42778 Da |
| Function | Calcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and autophagy. Capable of regulating both type I apoptotic and type II autophagic cell deaths signal. The former involves caspase activation, chromatin and mitochondrial condensation while the latter involves caspase-independent cell death in conjunction with accumulation of mature autophagic vesicles, plasma membrane blebs, and nuclear condensation without DNA degradation. Mediator of anoikis and a suppressor of beta- catenin-dependent anchorage-independent growth of malignant epithelial cells. May play a role in granulocytic maturation (By similarity) |
| Tissue Specificity | Isoform 1 is found in the adult brain while isoform 2 is expressed in brains of embryos and young mice (at protein level) |
| Cellular Localization | Cytoplasm (By similarity). Cytoplasmic vesicle, autophagosome lumen (By similarity) |
| Entrez Gene | 13143 |
|---|---|
| Nucleotide Accession | NP_034149.2 |
Application
Mouse Dapk2 Antibody (N-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the Dapk2 antibody detected the Dapk2 protein (arrow).
Application
Western blot analysis of Dapk2 (arrow) using rabbit polyclonal Mouse Dapk2 Antibody (N-term) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the Dapk2 gene.| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
