Application
Mouse Derl2 Antibody (C-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the Derl2 antibody detected the Derl2 protein (arrow).| Product Name | Derl2 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Derl2; Der2; Flana; Derlin-2; Degradation in endoplasmic reticulum protein 2; Der1-like protein 2; F-LANa |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | Der2 Flana |
|---|---|
| Alternative Names | Derl2 Der2 Flana Derlin-2 Degradation in endoplasmic reticulum protein 2 Der1-like protein 2 F-LANa |
| Molecular Weight(MW) | 27640 Da |
| Function | Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal glycoproteins, but not that of misfolded nonglycoproteins. May act by forming a channel that allows the retrotranslocation of misfolded glycoproteins into the cytosol where they are ubiquitinated and degraded by the proteasome. May mediate the interaction between VCP and the degradation substrate (By similarity) |
| Tissue Specificity | Widely expressed, with lowest levels in brain and heart |
| Cellular Localization | Endoplasmic reticulum membrane; Multi-pass membrane protein (By similarity) |
| Entrez Gene | 116891 |
|---|---|
| Nucleotide Accession | NP_291040.1 |
Application
Mouse Derl2 Antibody (C-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the Derl2 antibody detected the Derl2 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
