Application
Mouse Dyrk1b Antibody (Center) western blot analysis in mouse lung tissue lysates (35ug/lane).This demonstrates the Dyrk1b antibody detected the Dyrk1b protein (arrow).| Product Name | Dyrk1b Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Dyrk1b; Dual specificity tyrosine-phosphorylation-regulated kinase 1B |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | Dyrk1b Dual specificity tyrosine-phosphorylation-regulated kinase 1B |
|---|---|
| Molecular Weight(MW) | 69178 Da |
| Function | Dual-specificity kinase which possesses both serine/ threonine and tyrosine kinase activity. Enhances the transcriptional activity of TCF1/HNF1A and FOXO1. Inhibits epithelial cell migration. Mediates colon carcinoma cell survival in mitogen-poor environments |
| Tissue Specificity | Isoform 1 and isoform 2 are broadly expressed. Isoform 3 seems specific for skeletal muscle (at protein level) |
| Cellular Localization | Nucleus. |
| Entrez Gene | 13549 |
|---|---|
| Nucleotide Accession | NP_001033046.1 NP_034222.1 |
Application
Mouse Dyrk1b Antibody (Center) western blot analysis in mouse lung tissue lysates (35ug/lane).This demonstrates the Dyrk1b antibody detected the Dyrk1b protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
