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EphA6 Antibody (N-term)

Catalog Number:OM214112
OM214112
Discount Price
OM214112-100ul
1~2 Week
100ul
OM214112-50ul
50ul
OM214112-20ul
20ul
1~2 Week
Product Profile
Product Name EphA6 Antibody (N-term)
Antibody Type Primary Antibodies
Antigen Alias Epha6; Ehk-2; Ehk2; Ephrin type-A receptor 6; EPH homology kinase 2
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WBIHC
WB:1:100~500 IHC
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms Ehk-2
Ehk2
Alternative Names Epha6
Ehk-2
Ehk2
Ephrin type-A receptor 6
EPH homology kinase 2
Molecular Weight(MW) 116185 Da
Function Receptor tyrosine kinase which binds promiscuously GPI- anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling (By similarity)
Tissue Specificity This Mouse EphA6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 721~750 amino acids from the N-terminal region of mouse EphA6.
Cellular Localization Membrane; Single-pass type I membrane protein
Application

Application

Western blot analysis of anti-EphA6 N-term Pab in Jurkat cell lysate. EphA6 (arrow) was detected using purified Pab. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.

Application

Formalin-fixed and paraffin-embedded human brain tissue reacted with Mouse EphA6 antibody (N-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Application Notes WB:1:100~500 IHC
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
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