| Product Name | GPR81-S296 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Hcar1; Gpr81; Hydroxycarboxylic acid receptor 1; G-protein coupled receptor 81 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | Gpr81 |
|---|---|
| Alternative Names | Hcar1 Gpr81 Hydroxycarboxylic acid receptor 1 G-protein coupled receptor 81 |
| Molecular Weight(MW) | 38927 Da |
| Function | Acts as a receptor for L-lactate and mediates its anti- lipolytic effect through a G(i)-protein-mediated pathway |
| Tissue Specificity | Highly expressed in subcutaneous fat and omental fat and detectable in lower levels in brain and many other tissues. High levels detected in epididymal and subcutaneous fat with slightly lower in omental fat, low levels are detected in the brain, skeletal muscle, kidney, liver and the pancreas (at protein level) |
| Cellular Localization | Cell membrane; Multi-pass membrane protein. |
| Nucleotide Accession | NP_780729 |
|---|
| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is first purified by protein A affinity chromatography. Then, the antibody fraction is peptide affinity purified in a 2-step procedure with peptides. The antibody is eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
