Application
Mouse Frk Antibody (C-term) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the Frk antibody detected the Frk protein (arrow).| Product Name | Frk Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Frk; Bsk; Iyk; Tyrosine-protein kinase FRK; Beta-cell Src-homology tyrosine kinase; FYN-related kinase; Intestine tyrosine kinase |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | Bsk Iyk |
|---|---|
| Alternative Names | Frk Bsk Iyk Tyrosine-protein kinase FRK Beta-cell Src-homology tyrosine kinase FYN-related kinase Intestine tyrosine kinase |
| Molecular Weight(MW) | 58844 Da |
| Function | Non-receptor tyrosine-protein kinase that negatively regulates cell proliferation. Positively regulates PTEN protein stability through phosphorylation of PTEN on 'Tyr-336', which in turn prevents its ubiquitination and degradation, possibly by reducing its binding to NEDD4. May function as a tumor suppressor (By similarity) |
| Tissue Specificity | Expressed in intestinal tract, fetal and adult islets of Langerhans, kidney, liver and lung |
| Cellular Localization | Cytoplasm (By similarity). Nucleus (By similarity). Note=Predominantly found in the nucleus, with a small fraction found in the cell periphery (By similarity) |
| Entrez Gene | 14302 |
|---|---|
| Nucleotide Accession | NP_034367.2 NP_001153016.1 |
Application
Mouse Frk Antibody (C-term) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the Frk antibody detected the Frk protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
